Little is known about their social structure, but they are known to communicate by scent marking. Males are highly territorial. Slow lorises reproduce slowly, and the infants are initially parked on branches or carried by either parent. They are omnivores, eating small animals, fruit, tree gum, and other vegetation.
Each of the slow loris species that had been identified prior to 2012 is listed as either "Vulnerable" or "Endangered" on the IUCN Red List. The three newest species are yet to be evaluated, but they arise from (and further reduce the ranks of) what was thought to be a single "vulnerable" species. All four of these are expected to be listed with at least the same, if not a higher-risk, conservation status. All slow lorises are threatened by the wildlife trade and habitat loss. Their habitat is rapidly disappearing and becoming fragmented, making it nearly impossible for slow lorises to disperse between forest fragments; unsustainable demand from the exotic pet trade and from traditional medicine has been the greatest cause for their decline.
Deep-rooted beliefs about the supernatural powers of slow lorises, such as their purported abilities to ward off evil spirits or to cure wounds, have popularized their use in traditional medicine. Despite local laws prohibiting trade in slow lorises and slow loris products, as well as protection from international commercial trade under Appendix I, slow lorises are openly sold in animal markets in Southeast Asia and smuggled to other countries, such as Japan. Due in part to the large eyes that are an adaptation to their nocturnal lifestyle, they have also been popularized as 'cute' pets in viral videos on YouTube. Slow lorises have their teeth cut or pulled out for the pet trade. They make poor pets as they are nocturnal, have specialized diets, are difficult to care for, and often die from infection, blood loss, improper caring and handling or inadequate nutrition.