The Greater Mouse-deer is an even-toed ungulate. Although very small for an ungulate, the greater mouse-deer is one of the largest members of its genus. It is rivalled in size by Williamson's mouse-deer. It weighs 5 to 8 kg (11 to 18 lb). Its head-and-body length is 70 to 75 cm (2.30 to 2.46 ft) and its tail length is 8 to 10 cm (3.1 to 3.9 in). Its shoulder height is about 30 to 35 cm (12 to 14 in) It has a small, triangular head with a small, pointed, black nose and large eyes. Its long legs are as thin as a pencil. The hind legs are visibly longer than the front legs. The body is rounded. The fur on the upper part of its body is grey-buff to orange-buff. On the sides, the fur is quite pale, but darker along the midline. It is white underneath, more specifically on the neck, stomach, chest, and chin. The male has neither horns nor antlers, but has small "tusks" – elongated canines in the upper jaws.
Greater mouse-deer are found in Sumatra, Borneo, and smaller Malaysian and Indonesian islands, and in southern Myanmar, southern Thailand, and peninsular Malaysia. They live near water, in tropical forests and mangrove thickets. Thought to be regionally extinct in Singapore, they were rediscovered on an offshore island in 2008. Reports of its occurrence elsewhere are probably incorrect. They are terrestrial, but spend time in wet, swampy areas.
The greater mouse-deer is solitary and nocturnal. It uses small trails through thick brush in the forest. When the male is ready to mate, he rubs a large gland on his lower jaw against the female to determine whether she is ready to mate. If she is not ready, she responds by walking away. The male is very territorial, marking his territory with feces, urine, and secretions from the intermandibular gland under the chin. When angry, the male beats the ground with his hooves at a rate of four times per second.
They are rather trusting but delicate animals. They feed on fallen fruits, aquatic plants, buds, leaves, shrubs and grasses.
Greater mouse-deer breed throughout the year; the female spends most of her adult life pregnant. They usually produce one young per birth, after a gestation of 152–155 days. Newborn animals are well-developed and immediately able to stand; they are fully active after 30 minutes. The young stand on three legs while nursing. Both male and female become mature at age 4½ months. Their lifespan is up to 14 years.